The Print tool gives you a variety of printing options. Not every printing option is available for every block. Some blocks are not ideal for foundation piecing or for rotary cutting. These options will be disabled if they are not available for a block. The template option is never disabled. You will always be able to print templates and colored or grayscale printouts for every block.
Printing gives you the option to Use size from quilt. This is very beneficial when you are printing a block pattern specific to the quilt you are going to make. Whatever size your layout is set at, is the size the designs will print if you choose this option.