From the Home Screen

When EQ8 opens, the home screen is displayed. From here it is easy to start a new quilt. Select Design a quilt from scratch in the DESIGN QUILTS section. This will display the NEW QUILT tab of the Quilt Worktable.

new quilt from home screen

From any Worktable in EQ8

You can always start a new quilt by clicking the Quilt Worktable button, then selecting the NEW QUILT tab.

Quilt Worktable Button